LDDA(5)


 Software for analysis of data obtained with Laser Doppler instruments (e.g. the Laser Doppler Blood Perfusion Monitor from the Moor Instruments® or the PeriFlux® family manufactured by Perimed®, Sweden) for evaluation of microvascular perfusion.

 
 

   

A file containing Laser Doppler data in binary or text format is required. The product is compatible with all recent versions of Nevrokard® LDDA(5) and PeriSoft® software.



Either whole or segmented recordings can be analyzed both in time and frequency domains.
 
  TIME DOMAIN ANALYSIS


Digital filtering of input data: Low Pass, Band Pass and High Pass Filters.



   

Statistics: Max., Min., Max./Min., Range, Mean, Median, 95% Conf. Interval, 99% Conf. Interval, Coef. of Variance, Variance, SDNN, SENN, SDSD, RMSSD.

   

Segmented Statistics: SDANN, SDNN Index, t-test between segments; Mean, STD, SE, 95% Confidence Interval and 99 % Confidence Interval for each segment.

   

Linear Regression (Trend Analysis): Coefficients A and B, R2, SEE.

   

Histogram: Mean, SD, Median, Modus, Dispersion, Upper F(X), Uncertainty, Skeweness, Kurtosis and Variability Index (HRV Triangular Index with a freely adjustable Class Interval (bin value)).

 
  FREQUENCY DOMAIN ANALYSIS
 
Based on the Autoregressive Model (parametric method):
  • Frequency domain analysis of up to 5Hz for all compatible files.
  • Spectral density units: absolute, normalized.
  • Freely adjustable model order.
  • Graphic presentation and calculation of integrals of up to 5 preset frequency bands (ULF, VLF, LF, HF, VHF) which represent the quantitative, numeric results of spectral analysis and give a measure of microcirculation in absolute or normalized units (absolute power of given component/[sum of absolute powers of all components-F*] x 100, *F=adjustable low frequency limit for n.u. calculation).
  • On-screen determination of spectral density at any frequency.
  • LF/HF ratio, LF/(LF+HF) ratio, HF/(LF+HF) ratio, CCVLF (Coefficient of Component Variance for LF) and CCVHF (Coefficient of Component Variance for HF).



Based on the FFT Algorithm (non-parametric method):
  • Frequency domain analysis of up to 5Hz for all compatible files.
  • FFT spectra types: Amplitude (= Magnitude), RMS, Power.
  • FFT window types: Rectangular, Hanning, Hamming, Flat Top, Bartlet, Blackman, Exponent, Blackman Exact, Blackman Harris, Chebyshev, Cosine Tappered, Kaiser.
  • Spectral density units: absolute, normalized.
  • Absolute units: linear, logarithmic (absolute, relative).
  • Smoothing with triangular window (freely adjustable smooth index).
  • Graphic presentation and calculation of integrals of up to 5 preset frequency bands (ULF, VLF, LF, HF, VHF) which represent the quantitative, numeric results of spectral analysis and give a measure of microcirculation in absolute or normalized units (absolute power of given component/[sum of absolute powers of all components-F*] x 100, *F=adjustable low frequency limit for n.u. calculation).
  • On-screen determination of spectral density at any frequency.
  • LF/HF ratio, LF/(LF+HF) ratio, HF/(LF+HF) ratio, CCVLF (Coefficient of Component Variance for LF) and CCVHF (Coefficient of Component Variance for HF).



 
  RESULTS OF ANALYSIS
   

  • Results of analysis can be exported, directly converted into graphic formats or presentation slides, transferred to clipboard etc.